Faculty in Metabolic Regulation

 TB Research at Colorado State UniversityJohn Belisle
Professor (Microbiology, Immunology and Pathology). The provision of reagents and collaborations with other researchers through the Tubculosis Research Materials and Vaccine Testing Contract (NO1-AI-75320) The study of mycobacterial physiology and genetics.



chicco1Adam Chicco
Associate Professor (Biomedical Sciences); Ph.D. University of Northern Colorado 2004. How changes in cardiac fatty acid metabolism and mitochondrial dysfunction contribute to the development and/or progression of heart disease, and how dietary and pharmaceutical interventions may modulate these processes.



Crans1Debbie C. Crans
Professor (Chemistry); Ph.D. Harvard 1985. Biological chemistry; vanadium and transition metal chemistry relating to insulin mimetic effects; vanadium compounds with bone stimulating activities; enzyme mechanisms; phosphorus metabolism.



Florant1Gregory L. Florant
Professor (Biology); Ph.D. Stanford 1978. Mammalian physiology; lipid metabolism and energetics.




Colorado State UniversityMichelle T. Foster
Assistant Professor (Food Science and Human Nutrition); Ph.D Georgia State University, 2005. We have demonstrated that negative consequences of central obesity are attributed to depot location and adipocyte specific characteristics, but not fat mass.  Adipose depot characteristics proposed to play a role in obesity-induced co-morbities include, but are not limited to, protein release, lipid regulation, expansion capacity and inflammation response. The over all objective is to determine the differential mechanisms between the “pear” distribution that is protective against obesity-induced metabolic disorders and the “apple” distribution that is deleterious.


Frisbie1David D. Frisbie
Associate Professor (Biomedical Sciences); Ph.D.; Colorado State University, 1999. In vitro and in vivo approaches to diagnostic and therapeutic musculoskeletal disease with an emphasis on molecular and surgical techniques.




Melinda Frye
Assistant Professor (Biomedical Sciences); Ph.D., Colorado State University. Under conditions of dietary fatty acid manipulation in the rat: development of lipidomic strategies to study changes in cardiomyocyte and coronary microvascualar endothelial cell eicosanoid synthesis and oxidation, and measurement of associated functional changes in vivo using echocardiography. Optimization of the dietary obese rodent model to study the role of the visceral adipose in obesity cardiomyopathy. Investigation of lipid-mediated cardiac and endothelial dysfunction in veterinary patients.


Gentile1Chris Gentile
Assistant Professor (Food Science & Human Nutrition); Ph.D. Virginia Tech 2006.  The role of ER stress in obesity-related endothelial dysfunction Overview: The goal of the proposed studies is to examine the role of ER stress in obesity-related endothelial dysfunction and ER stress



Hamilton1Karyn Hamilton
Associate Professor (Health & Exercise Science); PhD., University of Florida, 2000. Mechanism(s) of exercise- and estrogen-induced protection of the heart and vascular endothelium against hypoxia-reoxygenation injury.



Henry1Charles S. Henry
Professor (Chemistry); Ph.D., Arkansas, 1998.  Bioanalytical chemistry; chemical separations and chemical nature of disease.





Matthew S. Hickey
Professor (Health & Exercise Science); PhD. Ball State University, 1993. The role of changes in dietary fat type (i.e., increased omega-3 fatty acids or decreased saturated fat) on insulin sensitivity and markers of both subclinical inflammation and endothelial dysfunction. Post-receptor signaling events in human skeletal muscle (i.e., insulin signaling, translation initiation) in response to changes in diet and physical activity. Ethnic differences in risk for the metabolic syndrome, diabetes, and cardiovascular disease. Diet, exercise, and nutrient partitioning.


Kanatous1Shane Kanatous
Associate Professor (Biology); Ph.D. Texas A & M University, 1997.  Enhance our understanding of molecular changes associated with hypoxia and translate these results for therapeutic applications in the treatment of myopathies.



Miller1Ben Miller
Associate Professor (Health & Exercise Science); PhD., University of California-Berkeley, 2002.  Aging skeletal muscle and the regulation of mitochondrial and protein turnover.



Mykles1Donald L. Mykles
Professor (Biology); Ph.D. California (Berkeley) 1979. Regulation of protein turnover; calcium-dependent and ATP/ubiquitin-dependent proteinases; myofibrillar proteins.



Pagliassotti1Michael J. Pagliassotti
Professor (Food Science & Human Nutrition); Ph.D. University of Southern California, 1988.  Nutrient regulation of hepatic glucose metabolism and gene expression.



Peebles1Christie Peebles
Assistant Professor (Chemical and Biological Engineering); Ph.D., Rice University, 2008. The use of plant metabolic engineering to produce important pharmaceuticals and nutraceuticals.  The engineering of photoautotrophs for the production of bio-based chemicals and fuels.



Peers1Graham Peers
Assistant Professor (Biology); Ph.D., McGill University, 2005. Nearly every biome on earth relies on photosynthesis to supply energy to its communities. While we are more familiar with the vascular plants that dominate the terrestrial environment, the algae rule aquatic systems. There is incredible diversity within the algae and they have evolved separately from plants (and in some cases from each other) for more than a billion years.  The research explores this variety and strives to discover how the processes of photosynthesis differ between groups.


Jessica PrenniJessica Prenni
Joint Faculty, Associate Professor, Director Of Research Core Facilities, Director of Proteomics & Metabolomics Facility
Ph.D., University of Colorado
Mass Spectrometry Based Proteomics and Metabolomics
Proteomics and Metabolomics are fields of scientific study which combine techniques in purification and separation, mass spectrometry and bioinformatics. In our lab we utilize these tools for the identification and characterization of proteins and small molecules in a variety of biological systems.


PrasadAshok Prasad
Assistant Professor (Chemical and Biological Engineering and School of Biomedical Engineering); Ph.D. Brandeis University, 2006. Mathematical and computational modeling of signal transduction and gene transcription, stochastic processes in biology, properties and dynamics of the cytoskeleton of mammalian cells, cancer drug sensitivity and resistance, modeling for synthetic biology applications in plants and single cells,  genome-scale metabolic modeling of e. coli, cyanobacteria and algae.

Reardon1Kenneth Reardon
Professor & Associate Department Head (Chemical Engineering); Ph.D. California Institute of Technology 1988. Proteomics, systems biology, metabolic engineering, and enzyme-based biosensors.



SantangeloThomas Santangelo
Assistant Professor (Biochemistry and Molecular Biology); Ph.D Cornell University. Mechanisms and regulation of archaeal transcription.



Thompson1Henry J. Thompson
Professor (Horticulture & Landscape Architecture and Head of the Cancer Prevention Laboratory); Ph.D. Rutgers 1975.  Biochemical and molecular approaches to cancer prevention; preclinical models and clinical investigations.



Weir1Tiffany Weir
Assistant Professor (Food Science & Human Nutrition); Ph.D Colorado State University, 2008. The role of microbes in ecosystem functioning, with ecosystems ranging from soils to processed food products to the human gut.



Wilusz C1Carol Wilusz
Associate Professor (Microbiology, Immunology & Pathology); Ph.D Imerial College, London. Post-transcriptional control of gene expression in myotonic dystrophy. Interactions between viruses and the cellular mRNA decay machinery.